2021 FBS Independents Leaders Opponent Penalties - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Notre Dame | 10 | 68 | 537 | 6.8 | 53.7 |
| 2 | BYU | 7 | 42 | 319 | 6.0 | 45.6 |
| 3 | Massachusetts | 3 | 17 | 170 | 5.7 | 56.7 |
| 4 | Connecticut | 3 | 16 | 152 | 5.3 | 50.7 |
| 5 | Army | 3 | 15 | 126 | 5.0 | 42.0 |
| 6 | Liberty | 2 | 14 | 116 | 7.0 | 58.0 |
| 7 | New Mexico State | 2 | 11 | 118 | 5.5 | 59.0 |