2021 FBS Independents Leaders Total Defense - Games in October Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Army | 3 | 414 | 803 | 164 | 1217 | 7.42 | 405.7 |
| 2 | New Mexico State | 3 | 540 | 875 | 188 | 1415 | 7.53 | 471.7 |
| 3 | Notre Dame | 4 | 573 | 1124 | 275 | 1697 | 6.17 | 424.3 |
| 4 | Connecticut | 4 | 616 | 1002 | 317 | 1618 | 5.10 | 404.5 |
| 5 | BYU | 5 | 783 | 1346 | 355 | 2129 | 6.00 | 425.8 |
| 6 | Liberty | 5 | 800 | 893 | 365 | 1693 | 4.64 | 338.6 |
| 7 | Massachusetts | 4 | 951 | 990 | 249 | 1941 | 7.80 | 485.3 |