2021 Independent Leaders Total Defense - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Army | 10 | 1137 | 2253 | 572 | 3390 | 5.93 | 339.0 |
| 2 | Liberty | 11 | 1389 | 2168 | 735 | 3557 | 4.84 | 323.4 |
| 3 | Massachusetts | 8 | 1887 | 1996 | 534 | 3883 | 7.27 | 485.4 |
| 4 | Connecticut | 10 | 1682 | 2829 | 767 | 4511 | 5.88 | 451.1 |
| 5 | Notre Dame | 13 | 1761 | 2915 | 887 | 4676 | 5.27 | 359.7 |
| 6 | BYU | 13 | 2042 | 3015 | 880 | 5057 | 5.75 | 389.0 |
| 7 | New Mexico State | 11 | 2068 | 3369 | 740 | 5437 | 7.35 | 494.3 |