2021 Independent Leaders Passes Defended - Games in October Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Malik Moore | BYU | JR | DB | 5 | 2 | 3 | 5 | 1.00 |
| 1 | Tre Wortham | UConn | JR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 1 | Payton Wilgar | BYU | SO | LB | 5 | 2 | 0 | 2 | 0.40 |
| 4 | Duron Lowe | Liberty | SR | CB | 5 | 1 | 4 | 5 | 1.00 |
| 4 | Bryce Watts | U Mass | JR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 4 | Jakob Robinson | BYU | FR | DB | 5 | 1 | 3 | 4 | 0.80 |
| 4 | Bo Bauer | Notre Dame | SR | LB | 4 | 1 | 2 | 3 | 0.75 |
| 4 | Daijahn Anthony | Liberty | SO | CB | 5 | 1 | 2 | 3 | 0.60 |
| 4 | Javon Scruggs | Liberty | JR | S | 5 | 1 | 2 | 3 | 0.60 |
| 4 | Storey Jackson | Liberty | SR | LB | 5 | 1 | 2 | 3 | 0.60 |
| 4 | Donte Lindsey | U Mass | SO | CB | 3 | 1 | 1 | 2 | 0.67 |
| 4 | Caleb Mills | NMSU | SR | DB | 3 | 1 | 1 | 2 | 0.67 |
| 4 | Jackson Mitchell | UConn | SO | LB | 4 | 1 | 1 | 2 | 0.50 |
| 4 | DJ Brown | Notre Dame | JR | S | 4 | 1 | 1 | 2 | 0.50 |
| 4 | Skyler Thomas | Liberty | SR | S | 5 | 1 | 1 | 2 | 0.40 |
| 4 | Robert Rahimi | Liberty | FR | S | 5 | 1 | 1 | 2 | 0.40 |
| 4 | Durante Jones | UConn | FR | DB | 4 | 1 | 0 | 1 | 0.25 |
| 4 | Tui Faumuina-Brown | UConn | FR | LB | 4 | 1 | 0 | 1 | 0.25 |
| 4 | TaRiq Bracy | Notre Dame | SR | CB | 4 | 1 | 0 | 1 | 0.25 |
| 4 | Drew Jensen | BYU | SO | LB | 5 | 1 | 0 | 1 | 0.20 |