2021 FBS Independents Leaders All Purpose - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brian Brewton | UConn | FR | RB | 2 | 0 | 27 | 0 | 190 | 7 | 217 | 31.0 | 108.5 |
| 2 | Shedro Louis | Liberty | SO | RB | 2 | 117 | 84 | 0 | 160 | 24 | 361 | 15.0 | 180.5 |
| 3 | Chris Tyree | Notre Dame | SO | RB | 2 | 38 | 123 | 0 | 131 | 25 | 292 | 11.7 | 146.0 |
| 4 | Juwaun Price | NMSU | FR | RB | 4 | 105 | 36 | 0 | 89 | 53 | 230 | 4.3 | 57.5 |
| 5 | Aaron Turner | UConn | FR | WR | 2 | 0 | 66 | 0 | 51 | 10 | 117 | 11.7 | 58.5 |
| 6 | Kay'Ron Adams | U Mass | SO | RB | 1 | 32 | 14 | 0 | 47 | 18 | 93 | 5.2 | 93.0 |
| 7 | Demario Douglas | Liberty | FR | WR | 2 | 0 | 90 | 0 | 42 | 10 | 132 | 13.2 | 66.0 |
| 8 | Tyrell Robinson | Army | SO | RB | 1 | 98 | 33 | 0 | 32 | 15 | 163 | 10.9 | 163.0 |
| 9 | Kevin Mensah | UConn | SR | RB | 2 | 29 | 8 | 0 | 25 | 28 | 62 | 2.2 | 31.0 |
| 10 | Lopini Katoa | BYU | JR | RB | 3 | 40 | 7 | 0 | 22 | 20 | 69 | 3.5 | 23.0 |
| 11 | Jamir Roberts | U Mass | FR | WR | 1 | 0 | 0 | 0 | 20 | 1 | 20 | 20.0 | 20.0 |
| 12 | Hobbs Nyberg | BYU | FR | WR | 3 | 0 | 0 | 43 | 14 | 6 | 57 | 9.5 | 19.0 |
| 13 | Duron Lowe | Liberty | SR | CB | 2 | 0 | 0 | 0 | 11 | 1 | 11 | 11.0 | 5.5 |
| 14 | Brandon Niemenski | UConn | FR | TE | 2 | 0 | 7 | 0 | 10 | 2 | 17 | 8.5 | 8.5 |
| 15 | Cedric Stone | Liberty | SR | S | 2 | 0 | 0 | 0 | 8 | 1 | 8 | 8.0 | 4.0 |