2021 Pac-12 Conference Leaders Sacks - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Utah | 11 | 38.0 | 253 | 3.46 |
| 2 | California | 10 | 23.0 | 168 | 2.30 |
| 3 | UCLA | 10 | 21.0 | 160 | 2.10 |
| 4 | USC | 9 | 19.0 | 99 | 2.11 |
| 5 | Arizona State | 10 | 18.0 | 123 | 1.80 |
| 5 | Arizona | 9 | 18.0 | 109 | 2.00 |
| 5 | Oregon | 12 | 18.0 | 106 | 1.50 |
| 8 | Washington State | 9 | 17.0 | 113 | 1.89 |
| 9 | Washington | 10 | 16.0 | 91 | 1.60 |
| 10 | Stanford | 11 | 13.0 | 85 | 1.18 |
| 11 | Oregon State | 10 | 10.0 | 58 | 1.00 |
| 11 | Colorado | 11 | 10.0 | 35 | 0.91 |