2021 Pac-12 Conference Leaders Total Offense - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | USC | 3 | 431 | 948 | 228 | 1379 | 6.05 | 459.7 |
| 2 | Oregon State | 3 | 497 | 779 | 186 | 1276 | 6.86 | 425.3 |
| 3 | Arizona State | 2 | 309 | 502 | 128 | 811 | 6.34 | 405.5 |
| 4 | California | 1 | 155 | 249 | 81 | 404 | 4.99 | 404.0 |
| 5 | UCLA | 2 | 256 | 507 | 170 | 763 | 4.49 | 381.5 |
| 6 | Oregon | 4 | 597 | 920 | 257 | 1517 | 5.90 | 379.3 |
| 7 | Utah | 5 | 888 | 989 | 340 | 1877 | 5.52 | 375.4 |
| 8 | Arizona | 4 | 436 | 984 | 293 | 1420 | 4.85 | 355.0 |
| 9 | Washington State | 4 | 403 | 987 | 257 | 1390 | 5.41 | 347.5 |
| 10 | Washington | 2 | 105 | 404 | 120 | 509 | 4.24 | 254.5 |
| 11 | Stanford | 3 | 261 | 487 | 172 | 748 | 4.35 | 249.3 |
| 12 | Colorado | 2 | 183 | 308 | 118 | 491 | 4.16 | 245.5 |