2021 Pac-12 Conference Leaders Opponent First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Washington | 1 | 5 | 9 | 1 | 15 | 15.0 |
| 2 | Utah | 2 | 23 | 7 | 3 | 33 | 16.5 |
| 3 | Arizona State | 2 | 17 | 13 | 4 | 34 | 17.0 |
| 4 | California | 1 | 5 | 12 | 2 | 19 | 19.0 |
| 5 | Arizona | 2 | 24 | 12 | 3 | 39 | 19.5 |
| 6 | Washington State | 3 | 31 | 30 | 3 | 64 | 21.3 |
| 7 | Oregon | 1 | 3 | 16 | 4 | 23 | 23.0 |
| 8 | USC | 3 | 25 | 39 | 7 | 71 | 23.7 |
| 9 | UCLA | 2 | 14 | 28 | 6 | 48 | 24.0 |
| 10 | Oregon State | 2 | 16 | 29 | 8 | 53 | 26.5 |
| 11 | Stanford | 1 | 10 | 13 | 4 | 27 | 27.0 |