2021 Pac-12 Conference Leaders Total Defense - Games in December/January Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | USC | 1 | 88 | 177 | 52 | 265 | 5.10 | 265.0 |
| 2 | Arizona State | 1 | 157 | 137 | 58 | 294 | 5.07 | 294.0 |
| 3 | Washington State | 1 | 147 | 209 | 73 | 356 | 4.88 | 356.0 |
| 4 | Oregon State | 1 | 110 | 273 | 75 | 383 | 5.11 | 383.0 |
| 5 | California | 1 | 144 | 265 | 79 | 409 | 5.18 | 409.0 |
| 6 | Utah | 2 | 184 | 720 | 120 | 904 | 7.53 | 452.0 |
| 7 | Oregon | 2 | 513 | 412 | 134 | 925 | 6.90 | 462.5 |