2021 Pac-12 Conference Leaders Opponent First Downs - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Utah | 9 | 60 | 95 | 11 | 166 | 18.4 |
| 2 | Washington State | 9 | 67 | 95 | 11 | 173 | 19.2 |
| 3 | Arizona | 8 | 69 | 58 | 22 | 149 | 18.6 |
| 3 | USC | 9 | 69 | 89 | 21 | 179 | 19.9 |
| 5 | UCLA | 10 | 75 | 109 | 25 | 209 | 20.9 |
| 5 | Oregon | 10 | 75 | 112 | 23 | 210 | 21.0 |
| 7 | Arizona State | 11 | 78 | 95 | 29 | 202 | 18.4 |
| 8 | Oregon State | 10 | 86 | 104 | 19 | 209 | 20.9 |
| 9 | Washington | 10 | 94 | 72 | 12 | 178 | 17.8 |
| 10 | California | 11 | 95 | 115 | 22 | 232 | 21.1 |
| 10 | Colorado | 10 | 95 | 98 | 19 | 212 | 21.2 |
| 12 | Stanford | 9 | 107 | 82 | 10 | 199 | 22.1 |