2021 Mid-American Conference Leaders Tackles For Loss - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Western Michigan | 10 | 78.0 | 345 | 7.80 |
| 2 | Central Michigan | 9 | 70.0 | 303 | 7.78 |
| 3 | Miami (Ohio) | 11 | 81.0 | 335 | 7.36 |
| 4 | Buffalo | 10 | 73.0 | 318 | 7.30 |
| 5 | Bowling Green | 9 | 63.0 | 220 | 7.00 |
| 6 | Toledo | 12 | 82.0 | 328 | 6.83 |
| 7 | Ball State | 11 | 59.0 | 205 | 5.36 |
| 8 | Kent State | 10 | 51.0 | 204 | 5.10 |
| 9 | Ohio | 9 | 43.0 | 155 | 4.78 |
| 10 | Northern Illinois | 11 | 52.0 | 181 | 4.73 |
| 11 | Eastern Michigan | 11 | 41.0 | 179 | 3.73 |
| 12 | Akron | 9 | 29.0 | 118 | 3.22 |