2021 Mid-American Conference Leaders Rushing Offense - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Kent State | 10 | 452 | 2533 | 5.60 | 28 | 45.20 | 253.30 |
| 2 | Toledo | 12 | 431 | 2353 | 5.46 | 25 | 35.92 | 196.08 |
| 3 | Northern Illinois | 11 | 526 | 2761 | 5.25 | 31 | 47.82 | 251.00 |
| 4 | Ohio | 9 | 347 | 1796 | 5.18 | 17 | 38.56 | 199.56 |
| 5 | Western Michigan | 10 | 459 | 2264 | 4.93 | 24 | 45.90 | 226.40 |
| 6 | Central Michigan | 9 | 356 | 1665 | 4.68 | 14 | 39.56 | 185.00 |
| 7 | Miami (Ohio) | 11 | 386 | 1586 | 4.11 | 11 | 35.09 | 144.18 |
| 8 | Buffalo | 10 | 450 | 1836 | 4.08 | 23 | 45.00 | 183.60 |
| 9 | Bowling Green | 9 | 279 | 1056 | 3.78 | 11 | 31.00 | 117.33 |
| 10 | Ball State | 11 | 378 | 1414 | 3.74 | 14 | 34.36 | 128.55 |
| 11 | Akron | 9 | 319 | 1172 | 3.67 | 6 | 35.44 | 130.22 |
| 12 | Eastern Michigan | 11 | 379 | 1304 | 3.44 | 21 | 34.45 | 118.55 |