2021 Mid-American Conference Leaders Tackles For Loss - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Central Michigan | 3 | 30.0 | 136 | 10.00 |
| 2 | Kent State | 3 | 16.0 | 31 | 5.33 |
| 3 | Bowling Green | 2 | 11.0 | 65 | 5.50 |
| 4 | Western Michigan | 2 | 10.0 | 45 | 5.00 |
| 4 | Miami (Ohio) | 1 | 10.0 | 24 | 10.00 |
| 6 | Northern Illinois | 2 | 8.0 | 31 | 4.00 |
| 7 | Ball State | 1 | 6.0 | 23 | 6.00 |
| 7 | Ohio | 2 | 6.0 | 14 | 3.00 |
| 9 | Buffalo | 1 | 5.0 | 8 | 5.00 |
| 10 | Akron | 2 | 4.0 | 19 | 2.00 |
| 11 | Eastern Michigan | 1 | 3.0 | 7 | 3.00 |