2021 Mid-American Conference Leaders Total Offense - Games in August/September Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Central Michigan | 4 | 719 | 1154 | 326 | 1873 | 5.75 | 468.3 |
| 2 | Western Michigan | 4 | 666 | 922 | 298 | 1588 | 5.33 | 397.0 |
| 3 | Toledo | 4 | 614 | 907 | 255 | 1521 | 5.96 | 380.3 |
| 4 | Bowling Green | 4 | 181 | 886 | 245 | 1067 | 4.36 | 266.8 |
| 5 | Eastern Michigan | 4 | 663 | 845 | 263 | 1508 | 5.73 | 377.0 |
| 6 | Miami (Ohio) | 4 | 530 | 844 | 242 | 1374 | 5.68 | 343.5 |
| 7 | Akron | 4 | 462 | 831 | 274 | 1293 | 4.72 | 323.3 |
| 8 | Buffalo | 4 | 752 | 822 | 293 | 1574 | 5.37 | 393.5 |
| 9 | Kent State | 4 | 950 | 807 | 300 | 1757 | 5.86 | 439.3 |
| 10 | Ball State | 4 | 525 | 746 | 285 | 1271 | 4.46 | 317.8 |
| 11 | Northern Illinois | 4 | 862 | 697 | 255 | 1559 | 6.11 | 389.8 |
| 12 | Ohio | 4 | 564 | 687 | 227 | 1251 | 5.51 | 312.8 |