2021 Mid-American Conference Leaders Rushing Offense - Games in August/September Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Eastern Michigan | 4 | 162 | 663 | 4.09 | 14 | 40.50 | 165.75 |
| 2 | Buffalo | 4 | 174 | 752 | 4.32 | 12 | 43.50 | 188.00 |
| 3 | Northern Illinois | 4 | 161 | 862 | 5.35 | 10 | 40.25 | 215.50 |
| 4 | Kent State | 4 | 195 | 950 | 4.87 | 8 | 48.75 | 237.50 |
| 4 | Western Michigan | 4 | 174 | 666 | 3.83 | 8 | 43.50 | 166.50 |
| 6 | Toledo | 4 | 141 | 614 | 4.35 | 6 | 35.25 | 153.50 |
| 7 | Miami (Ohio) | 4 | 131 | 530 | 4.05 | 5 | 32.75 | 132.50 |
| 7 | Ball State | 4 | 142 | 525 | 3.70 | 5 | 35.50 | 131.25 |
| 9 | Bowling Green | 4 | 110 | 181 | 1.65 | 4 | 27.50 | 45.25 |
| 10 | Central Michigan | 4 | 165 | 719 | 4.36 | 3 | 41.25 | 179.75 |
| 10 | Ohio | 4 | 115 | 564 | 4.90 | 3 | 28.75 | 141.00 |
| 10 | Akron | 4 | 156 | 462 | 2.96 | 3 | 39.00 | 115.50 |