2021 Mid-American Conference Leaders Tackles For Loss - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Central Michigan | 13 | 105.0 | 451 | 8.08 |
| 2 | Miami (Ohio) | 12 | 97.0 | 392 | 8.08 |
| 3 | Buffalo | 12 | 87.0 | 389 | 7.25 |
| 4 | Western Michigan | 11 | 86.0 | 381 | 7.82 |
| 5 | Bowling Green | 12 | 81.0 | 320 | 6.75 |
| 6 | Toledo | 12 | 79.0 | 298 | 6.58 |
| 7 | Kent State | 13 | 67.0 | 246 | 5.15 |
| 8 | Ball State | 13 | 69.0 | 243 | 5.31 |
| 9 | Northern Illinois | 13 | 62.0 | 215 | 4.77 |
| 9 | Eastern Michigan | 13 | 51.0 | 215 | 3.92 |
| 11 | Akron | 11 | 41.0 | 181 | 3.73 |
| 12 | Ohio | 11 | 51.0 | 165 | 4.64 |