2021 Mid-American Conference Leaders Total Defense - Games vs. FCS (I-AA) Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Buffalo | 1 | 18 | 79 | 50 | 97 | 1.94 | 97.0 |
| 2 | Western Michigan | 1 | 28 | 29 | 45 | 57 | 1.27 | 57.0 |
| 3 | Akron | 1 | 29 | 117 | 56 | 146 | 2.61 | 146.0 |
| 4 | Miami (Ohio) | 1 | 38 | 178 | 59 | 216 | 3.66 | 216.0 |
| 5 | Central Michigan | 1 | 54 | 55 | 38 | 109 | 2.87 | 109.0 |
| 6 | Bowling Green | 1 | 69 | 132 | 61 | 201 | 3.30 | 201.0 |
| 7 | Ball State | 1 | 70 | 367 | 67 | 437 | 6.52 | 437.0 |
| 8 | Eastern Michigan | 1 | 105 | 187 | 64 | 292 | 4.56 | 292.0 |
| 9 | Northern Illinois | 1 | 125 | 165 | 56 | 290 | 5.18 | 290.0 |
| 10 | Kent State | 1 | 138 | 146 | 73 | 284 | 3.89 | 284.0 |
| 11 | Toledo | 1 | 147 | 134 | 61 | 281 | 4.61 | 281.0 |
| 12 | Ohio | 1 | 168 | 194 | 79 | 362 | 4.58 | 362.0 |