2021 Mid-American Conference Leaders Rushing Defense - Games in December/January Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Central Michigan | 1 | 26 | 13 | 0.50 | 1 | 26.00 | 13.00 |
| 2 | Miami (Ohio) | 1 | 32 | 89 | 2.78 | 2 | 32.00 | 89.00 |
| 3 | Toledo | 1 | 44 | 159 | 3.61 | 2 | 44.00 | 159.00 |
| 4 | Western Michigan | 1 | 31 | 121 | 3.90 | 2 | 31.00 | 121.00 |
| 5 | Kent State | 2 | 113 | 677 | 5.99 | 10 | 56.50 | 338.50 |
| 6 | Ball State | 1 | 41 | 259 | 6.32 | 1 | 41.00 | 259.00 |
| 7 | Northern Illinois | 2 | 61 | 394 | 6.46 | 3 | 30.50 | 197.00 |
| 8 | Eastern Michigan | 1 | 35 | 233 | 6.66 | 3 | 35.00 | 233.00 |