2021 Mid-American Conference Leaders Rushing Defense - From Opponent's 1 To 20 Yard Line through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Ball State | 12 | 64 | 271 | 4.23 | 0 | 46 | 11 | 7 | 1 |
| 2 | Northern Illinois | 12 | 34 | 150 | 4.41 | 0 | 25 | 6 | 6 | 2 |
| 2 | Miami (Ohio) | 11 | 46 | 183 | 3.98 | 0 | 42 | 6 | 4 | 2 |
| 2 | Kent State | 13 | 40 | 238 | 5.95 | 1 | 80 | 9 | 4 | 2 |
| 2 | Central Michigan | 12 | 51 | 275 | 5.39 | 0 | 69 | 9 | 8 | 2 |
| 6 | Buffalo | 11 | 29 | 231 | 7.97 | 1 | 99 | 6 | 5 | 3 |
| 6 | Akron | 12 | 29 | 243 | 8.38 | 0 | 63 | 10 | 8 | 3 |
| 6 | Bowling Green | 11 | 53 | 253 | 4.77 | 0 | 54 | 11 | 7 | 3 |
| 6 | Ohio | 11 | 49 | 357 | 7.29 | 1 | 90 | 12 | 10 | 3 |
| 10 | Eastern Michigan | 12 | 43 | 326 | 7.58 | 1 | 82 | 9 | 9 | 4 |
| 11 | Western Michigan | 10 | 41 | 311 | 7.59 | 1 | 96 | 7 | 7 | 5 |
| 12 | Toledo | 13 | 54 | 412 | 7.63 | 0 | 52 | 14 | 15 | 6 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||