2021 Mid-American Conference Leaders Rushing - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | La'Darius Jefferson | W Mich | JR | RB | 2 | 32 | 116 | 3.63 | 3 | 16.00 | 58.00 |
| 2 | Sean Tyler | W Mich | SO | RB | 2 | 24 | 139 | 5.79 | 1 | 12.00 | 69.50 |
| 2 | Kenny Tracy | Miami (Oh) | FR | RB | 1 | 8 | 37 | 4.63 | 1 | 8.00 | 37.00 |
| 2 | Dequan Finn | Toledo | FR | QB | 1 | 2 | 24 | 12.00 | 1 | 2.00 | 24.00 |