2021 Big Ten Conference Leaders Tackles For Loss - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Michigan State | 11 | 75.0 | 348 | 6.82 |
| 2 | Wisconsin | 10 | 68.0 | 285 | 6.80 |
| 3 | Penn State | 11 | 70.0 | 284 | 6.36 |
| 4 | Ohio State | 11 | 65.0 | 300 | 5.91 |
| 5 | Purdue | 11 | 64.0 | 260 | 5.82 |
| 6 | Illinois | 10 | 58.0 | 248 | 5.80 |
| 7 | Nebraska | 10 | 55.0 | 234 | 5.50 |
| 8 | Michigan | 12 | 64.0 | 288 | 5.33 |
| 9 | Rutgers | 11 | 57.0 | 228 | 5.18 |
| 10 | Indiana | 9 | 44.0 | 167 | 4.89 |
| 11 | Maryland | 11 | 49.0 | 243 | 4.46 |
| 12 | Minnesota | 11 | 48.0 | 208 | 4.36 |
| 13 | Iowa | 12 | 48.0 | 221 | 4.00 |
| 14 | Northwestern | 10 | 39.0 | 133 | 3.90 |