2021 Big Ten Conference Leaders Passes Defended - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Ohio State | 9 | 6 | 48 | 54 | 6.00 |
| 2 | Iowa | 8 | 16 | 26 | 42 | 5.25 |
| 2 | Michigan | 9 | 6 | 36 | 42 | 4.67 |
| 4 | Indiana | 10 | 5 | 35 | 40 | 4.00 |
| 5 | Nebraska | 8 | 6 | 33 | 39 | 4.88 |
| 6 | Michigan State | 8 | 6 | 32 | 38 | 4.75 |
| 7 | Purdue | 8 | 6 | 27 | 33 | 4.13 |
| 8 | Penn State | 7 | 7 | 19 | 26 | 3.71 |
| 9 | Illinois | 7 | 6 | 19 | 25 | 3.57 |
| 9 | Wisconsin | 9 | 7 | 18 | 25 | 2.78 |
| 11 | Minnesota | 6 | 4 | 17 | 21 | 3.50 |
| 11 | Rutgers | 7 | 2 | 19 | 21 | 3.00 |
| 13 | Maryland | 6 | 1 | 15 | 16 | 2.67 |
| 14 | Northwestern | 6 | 2 | 13 | 15 | 2.50 |