2021 Big Ten Conference Leaders Total Offense - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Ohio State | 4 | 798 | 1627 | 279 | 2425 | 8.69 | 606.3 |
| 2 | Maryland | 4 | 739 | 1338 | 283 | 2077 | 7.34 | 519.3 |
| 3 | Michigan State | 4 | 713 | 1257 | 297 | 1970 | 6.63 | 492.5 |
| 4 | Purdue | 4 | 422 | 1513 | 312 | 1935 | 6.20 | 483.8 |
| 5 | Michigan | 4 | 1142 | 730 | 259 | 1872 | 7.23 | 468.0 |
| 6 | Penn State | 4 | 535 | 1182 | 273 | 1717 | 6.29 | 429.3 |
| 7 | Nebraska | 3 | 644 | 889 | 219 | 1533 | 7.00 | 511.0 |
| 8 | Wisconsin | 4 | 785 | 655 | 260 | 1440 | 5.54 | 360.0 |
| 9 | Rutgers | 4 | 544 | 785 | 279 | 1329 | 4.76 | 332.3 |
| 10 | Minnesota | 4 | 882 | 444 | 254 | 1326 | 5.22 | 331.5 |
| 11 | Iowa | 4 | 500 | 753 | 250 | 1253 | 5.01 | 313.3 |
| 12 | Indiana | 3 | 465 | 756 | 239 | 1221 | 5.11 | 407.0 |
| 13 | Illinois | 3 | 602 | 565 | 219 | 1167 | 5.33 | 389.0 |
| 14 | Northwestern | 3 | 739 | 414 | 204 | 1153 | 5.65 | 384.3 |