2021 Big Ten Conference Leaders Rushing Defense - Games in October Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Michigan State | 4 | 132 | 463 | 3.51 | 1 | 33.00 | 115.75 |
| 2 | Ohio State | 4 | 133 | 234 | 1.76 | 2 | 33.25 | 58.50 |
| 2 | Penn State | 4 | 170 | 697 | 4.10 | 2 | 42.50 | 174.25 |
| 4 | Minnesota | 4 | 119 | 435 | 3.66 | 3 | 29.75 | 108.75 |
| 4 | Rutgers | 4 | 153 | 699 | 4.57 | 3 | 38.25 | 174.75 |
| 6 | Wisconsin | 5 | 161 | 328 | 2.04 | 4 | 32.20 | 65.60 |
| 7 | Iowa | 4 | 131 | 456 | 3.48 | 5 | 32.75 | 114.00 |
| 7 | Nebraska | 4 | 152 | 539 | 3.55 | 5 | 38.00 | 134.75 |
| 7 | Illinois | 4 | 167 | 764 | 4.57 | 5 | 41.75 | 191.00 |
| 10 | Indiana | 4 | 155 | 575 | 3.71 | 6 | 38.75 | 143.75 |
| 10 | Purdue | 4 | 145 | 621 | 4.28 | 6 | 36.25 | 155.25 |
| 12 | Michigan | 4 | 123 | 482 | 3.92 | 7 | 30.75 | 120.50 |
| 13 | Maryland | 4 | 173 | 841 | 4.86 | 12 | 43.25 | 210.25 |
| 14 | Northwestern | 4 | 194 | 1092 | 5.63 | 15 | 48.50 | 273.00 |