2021 Big Ten Conference Leaders Passing Defense - Games in August/September Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Wisconsin | 3 | 90 | 49 | 54.4 | 562 | 6.2 | 3 | 1 | 115.67 | 30.0 | 187.3 |
| 2 | Rutgers | 4 | 100 | 48 | 48.0 | 600 | 6.0 | 1 | 3 | 95.70 | 25.0 | 150.0 |
| 3 | Michigan | 4 | 122 | 67 | 54.9 | 686 | 5.6 | 4 | 1 | 111.33 | 30.5 | 171.5 |
| 4 | Purdue | 4 | 122 | 64 | 52.5 | 707 | 5.8 | 2 | 2 | 103.27 | 30.5 | 176.8 |
| 5 | Iowa | 4 | 129 | 70 | 54.3 | 748 | 5.8 | 3 | 6 | 101.34 | 32.3 | 187.0 |
| 6 | Minnesota | 4 | 113 | 60 | 53.1 | 783 | 6.9 | 6 | 3 | 123.51 | 28.3 | 195.8 |
| 7 | Penn State | 4 | 155 | 93 | 60.0 | 818 | 5.3 | 2 | 5 | 102.14 | 38.8 | 204.5 |
| 8 | Northwestern | 4 | 138 | 90 | 65.2 | 842 | 6.1 | 3 | 3 | 119.29 | 34.5 | 210.5 |
| 9 | Maryland | 4 | 130 | 65 | 50.0 | 850 | 6.5 | 2 | 4 | 103.85 | 32.5 | 212.5 |
| 10 | Indiana | 4 | 147 | 87 | 59.2 | 916 | 6.2 | 6 | 1 | 123.63 | 36.8 | 229.0 |
| 11 | Nebraska | 5 | 156 | 98 | 62.8 | 943 | 6.0 | 5 | 5 | 117.77 | 31.2 | 188.6 |
| 12 | Ohio State | 4 | 148 | 80 | 54.1 | 1022 | 6.9 | 6 | 4 | 120.02 | 37.0 | 255.5 |
| 13 | Michigan State | 4 | 171 | 109 | 63.7 | 1056 | 6.2 | 5 | 4 | 120.58 | 42.8 | 264.0 |
| 14 | Illinois | 5 | 187 | 120 | 64.2 | 1562 | 8.4 | 9 | 3 | 147.01 | 37.4 | 312.4 |