2021 Big Ten Conference Leaders Passing Defense - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Wisconsin | 10 | 256 | 142 | 55.5 | 1642 | 6.4 | 4 | 15 | 102.79 | 25.6 | 164.2 |
| 2 | Minnesota | 11 | 323 | 181 | 56.0 | 1856 | 5.7 | 9 | 7 | 109.17 | 29.4 | 168.7 |
| 3 | Michigan | 10 | 307 | 165 | 53.7 | 1766 | 5.8 | 11 | 5 | 110.63 | 30.7 | 176.6 |
| 4 | Purdue | 9 | 242 | 139 | 57.4 | 1658 | 6.9 | 9 | 8 | 120.65 | 26.9 | 184.2 |
| 5 | Penn State | 8 | 296 | 171 | 57.8 | 1515 | 5.1 | 3 | 10 | 97.35 | 37.0 | 189.4 |
| 6 | Nebraska | 7 | 227 | 152 | 67.0 | 1394 | 6.1 | 10 | 6 | 127.79 | 32.4 | 199.1 |
| 7 | Maryland | 9 | 264 | 141 | 53.4 | 1880 | 7.1 | 7 | 5 | 118.19 | 29.3 | 208.9 |
| 8 | Iowa | 12 | 412 | 227 | 55.1 | 2520 | 6.1 | 13 | 22 | 106.21 | 34.3 | 210.0 |
| 9 | Rutgers | 9 | 259 | 140 | 54.1 | 1915 | 7.4 | 14 | 6 | 129.37 | 28.8 | 212.8 |
| 10 | Illinois | 11 | 345 | 207 | 60.0 | 2499 | 7.2 | 12 | 8 | 127.68 | 31.4 | 227.2 |
| 11 | Northwestern | 9 | 269 | 183 | 68.0 | 2074 | 7.7 | 10 | 6 | 140.60 | 29.9 | 230.4 |
| 12 | Indiana | 7 | 229 | 149 | 65.1 | 1757 | 7.7 | 16 | 1 | 151.70 | 32.7 | 251.0 |
| 13 | Ohio State | 9 | 344 | 218 | 63.4 | 2375 | 6.9 | 15 | 11 | 129.35 | 38.2 | 263.9 |
| 14 | Michigan State | 10 | 465 | 297 | 63.9 | 3197 | 6.9 | 17 | 7 | 130.67 | 46.5 | 319.7 |