2021 Big Ten Conference Leaders Passing Defense - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Wisconsin | 4 | 84 | 47 | 56.0 | 561 | 6.7 | 2 | 2 | 115.15 | 21.0 | 140.3 |
| 2 | Rutgers | 4 | 123 | 62 | 50.4 | 741 | 6.0 | 4 | 3 | 106.86 | 30.8 | 185.3 |
| 3 | Minnesota | 4 | 122 | 65 | 53.3 | 629 | 5.2 | 2 | 3 | 97.08 | 30.5 | 157.3 |
| 3 | Illinois | 3 | 95 | 65 | 68.4 | 894 | 9.4 | 8 | 2 | 171.05 | 31.7 | 298.0 |
| 5 | Maryland | 4 | 123 | 66 | 53.7 | 802 | 6.5 | 2 | 3 | 108.92 | 30.8 | 200.5 |
| 6 | Nebraska | 3 | 114 | 69 | 60.5 | 601 | 5.3 | 2 | 4 | 103.58 | 38.0 | 200.3 |
| 7 | Michigan | 4 | 122 | 70 | 57.4 | 861 | 7.1 | 7 | 1 | 133.96 | 30.5 | 215.3 |
| 8 | Iowa | 4 | 124 | 73 | 58.9 | 825 | 6.7 | 4 | 4 | 118.96 | 31.0 | 206.3 |
| 9 | Indiana | 3 | 119 | 74 | 62.2 | 771 | 6.5 | 6 | 1 | 131.57 | 39.7 | 257.0 |
| 10 | Northwestern | 3 | 112 | 75 | 67.0 | 657 | 5.9 | 2 | 3 | 116.76 | 37.3 | 219.0 |
| 11 | Purdue | 4 | 137 | 76 | 55.5 | 985 | 7.2 | 7 | 2 | 129.81 | 34.3 | 246.3 |
| 12 | Penn State | 4 | 138 | 85 | 61.6 | 731 | 5.3 | 2 | 5 | 103.61 | 34.5 | 182.8 |
| 12 | Ohio State | 4 | 147 | 85 | 57.8 | 1054 | 7.2 | 8 | 4 | 130.57 | 36.8 | 263.5 |
| 14 | Michigan State | 4 | 180 | 116 | 64.4 | 1183 | 6.6 | 6 | 4 | 126.20 | 45.0 | 295.8 |