2021 Big Ten Conference Leaders Passing Defense - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Iowa | 10 | 344 | 189 | 54.9 | 2178 | 6.3 | 12 | 21 | 107.42 | 34.4 | 217.8 |
| 2 | Wisconsin | 9 | 264 | 146 | 55.3 | 1705 | 6.5 | 7 | 14 | 107.69 | 29.3 | 189.4 |
| 3 | Illinois | 9 | 268 | 148 | 55.2 | 1688 | 6.3 | 4 | 7 | 107.84 | 29.8 | 187.6 |
| 4 | Michigan | 10 | 333 | 188 | 56.5 | 2001 | 6.0 | 10 | 7 | 112.65 | 33.3 | 200.1 |
| 5 | Penn State | 9 | 302 | 177 | 58.6 | 1867 | 6.2 | 9 | 9 | 114.41 | 33.6 | 207.4 |
| 6 | Minnesota | 9 | 247 | 140 | 56.7 | 1727 | 7.0 | 13 | 5 | 128.73 | 27.4 | 191.9 |
| 7 | Purdue | 9 | 237 | 146 | 61.6 | 1728 | 7.3 | 11 | 11 | 128.88 | 26.3 | 192.0 |
| 8 | Ohio State | 9 | 314 | 199 | 63.4 | 2142 | 6.8 | 13 | 8 | 129.24 | 34.9 | 238.0 |
| 9 | Nebraska | 9 | 290 | 192 | 66.2 | 2028 | 7.0 | 12 | 6 | 134.47 | 32.2 | 225.3 |
| 10 | Northwestern | 9 | 247 | 166 | 67.2 | 1941 | 7.9 | 9 | 3 | 142.82 | 27.4 | 215.7 |
| 11 | Michigan State | 9 | 399 | 264 | 66.2 | 3039 | 7.6 | 21 | 6 | 144.51 | 44.3 | 337.7 |
| 12 | Indiana | 9 | 266 | 166 | 62.4 | 2057 | 7.7 | 18 | 4 | 146.69 | 29.6 | 228.6 |
| 13 | Maryland | 9 | 287 | 175 | 61.0 | 2432 | 8.5 | 20 | 3 | 153.07 | 31.9 | 270.2 |
| 14 | Rutgers | 9 | 245 | 144 | 58.8 | 2313 | 9.4 | 21 | 4 | 163.09 | 27.2 | 257.0 |