2021 Big Ten Conference Leaders Rushing Defense - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Wisconsin | 9 | 265 | 535 | 2.02 | 7 | 29.44 | 59.44 |
| 2 | Ohio State | 9 | 298 | 1004 | 3.37 | 12 | 33.11 | 111.56 |
| 3 | Michigan State | 9 | 319 | 1116 | 3.50 | 7 | 35.44 | 124.00 |
| 4 | Iowa | 10 | 345 | 1219 | 3.53 | 12 | 34.50 | 121.90 |
| 5 | Michigan | 10 | 349 | 1243 | 3.56 | 10 | 34.90 | 124.30 |
| 6 | Penn State | 9 | 375 | 1337 | 3.57 | 6 | 41.67 | 148.56 |
| 7 | Illinois | 9 | 368 | 1391 | 3.78 | 12 | 40.89 | 154.56 |
| 8 | Nebraska | 9 | 328 | 1305 | 3.98 | 10 | 36.44 | 145.00 |
| 9 | Minnesota | 9 | 273 | 1095 | 4.01 | 7 | 30.33 | 121.67 |
| 10 | Indiana | 9 | 355 | 1501 | 4.23 | 19 | 39.44 | 166.78 |
| 11 | Purdue | 9 | 327 | 1442 | 4.41 | 13 | 36.33 | 160.22 |
| 12 | Rutgers | 9 | 361 | 1606 | 4.45 | 12 | 40.11 | 178.44 |
| 13 | Maryland | 9 | 364 | 1626 | 4.47 | 21 | 40.44 | 180.67 |
| 14 | Northwestern | 9 | 374 | 2138 | 5.72 | 28 | 41.56 | 237.56 |