2021 Big Ten Conference Leaders Long Receiving Plays - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Broc Thompson | Purdue | JR | WR | 11 | 11 | 4 | 3 | 2 | 2 | 2 | 2 | 0 | 0 |
| 1 | Samori Toure | Nebraska | SR | WR | 10 | 22 | 10 | 6 | 4 | 3 | 2 | 2 | 0 | 0 |
| 3 | Andrel Anthony | Michigan | FR | WR | 9 | 9 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Aron Cruickshank | Rutgers | JR | WR | 5 | 6 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Danny Davis III | Wisconsin | SR | WR | 9 | 15 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Jahan Dotson | Penn State | SR | WR | 10 | 39 | 14 | 9 | 4 | 1 | 1 | 1 | 1 | 0 |
| 3 | Donovan Edwards | Michigan | FR | RB | 10 | 7 | 3 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 3 | TreVeyon Henderson | Ohio State | FR | RB | 11 | 12 | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Charlie Jones | Iowa | SR | WR | 12 | 12 | 5 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Darryl Jones | Maryland | SR | WR | 11 | 9 | 7 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Jaxon Smith-Njigba | Ohio State | SO | WR | 11 | 55 | 25 | 12 | 8 | 5 | 1 | 1 | 0 | 0 |
| 3 | Garrett Wilson | Ohio State | JR | WR | 9 | 35 | 13 | 3 | 2 | 2 | 1 | 1 | 0 | 0 |
| 3 | Roman Wilson | Michigan | SO | WR | 11 | 11 | 8 | 5 | 2 | 1 | 1 | 1 | 0 | 0 |