2021 Big Ten Conference Leaders Interceptions - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Dane Belton | Iowa | JR | DB | 12 | 5 | 0 | 0 | 0.42 |
| 2 | Ji'Ayir Brown | Penn State | SR | S | 8 | 4 | 112 | 1 | 0.50 |
| 2 | Riley Moss | Iowa | SR | DB | 9 | 4 | 85 | 2 | 0.44 |
| 2 | Kerby Joseph | Illinois | JR | DB | 11 | 4 | 12 | 0 | 0.36 |
| 5 | Deontai Williams | Nebraska | SR | S | 5 | 3 | 11 | 0 | 0.60 |
| 5 | Collin Wilder | Wisconsin | SR | S | 8 | 3 | 53 | 0 | 0.38 |
| 5 | Max Melton | Rutgers | FR | DB | 9 | 3 | 46 | 1 | 0.33 |
| 5 | Brandon Joseph | N'western | SO | SAF | 9 | 3 | 26 | 0 | 0.33 |
| 5 | Jakorian Bennett | Maryland | SR | DB | 9 | 3 | -1 | 0 | 0.33 |
| 5 | John Torchio | Wisconsin | JR | S | 10 | 3 | 68 | 0 | 0.30 |
| 5 | Caesar Williams | Wisconsin | SR | CB | 10 | 3 | 49 | 1 | 0.30 |
| 5 | Matt Hankins | Iowa | SR | DB | 10 | 3 | 41 | 0 | 0.30 |
| 5 | Tyler Nubin | Minnesota | JR | DB | 11 | 3 | 42 | 0 | 0.27 |
| 14 | Jordan Turner | Wisconsin | FR | ILB | 5 | 2 | 6 | 0 | 0.40 |
| 14 | Craig Young | Ohio State | SO | SAF | 9 | 2 | 88 | 1 | 0.22 |
| 14 | Ronnie Hickman | Ohio State | SO | SAF | 9 | 2 | 65 | 1 | 0.22 |
| 14 | Jalen Graham | Purdue | JR | LB | 9 | 2 | 45 | 1 | 0.22 |
| 14 | Cam Allen | Purdue | JR | S | 9 | 2 | 31 | 0 | 0.22 |
| 14 | Nick Cross | Maryland | JR | DB | 9 | 2 | 10 | 0 | 0.22 |
| 14 | DJ Turner | Michigan | JR | DB | 10 | 2 | 65 | 1 | 0.20 |
| 14 | Daxton Hill | Michigan | JR | DB | 10 | 2 | 3 | 0 | 0.20 |
| 14 | Jermari Harris | Iowa | SO | DB | 10 | 2 | 0 | 0 | 0.20 |
| 14 | Jack Koerner | Iowa | SR | DB | 11 | 2 | 18 | 0 | 0.18 |
| 24 | Donte Burton | Wisconsin | JR | CB | 3 | 1 | 6 | 0 | 0.33 |
| 24 | Cameron Brown | Ohio State | JR | CB | 6 | 1 | 25 | 0 | 0.17 |
| 24 | JoJo Domann | Nebraska | SR | OLB | 6 | 1 | 0 | 0 | 0.17 |
| 24 | Quinn Schulte | Iowa | SO | DB | 7 | 1 | 42 | 0 | 0.14 |
| 24 | Raheem Layne | Indiana | SR | DB | 7 | 1 | 23 | 0 | 0.14 |
| 24 | Luke Reimer | Nebraska | SO | ILB | 7 | 1 | 22 | 0 | 0.14 |
| 24 | Jesse Luketa | Penn State | SR | DE | 7 | 1 | 16 | 1 | 0.14 |
| 24 | Curtis Jacobs | Penn State | SO | LB | 7 | 1 | 2 | 0 | 0.14 |
| 24 | Terry Roberts | Iowa | JR | DB | 7 | 1 | 0 | 0 | 0.14 |
| 24 | Cam Taylor-Britt | Nebraska | JR | CB | 7 | 1 | 0 | 0 | 0.14 |
| 24 | Jonathan Sutherland | Penn State | SR | S | 7 | 1 | 0 | 0 | 0.14 |
| 24 | Cameron Martinez | Ohio State | FR | SAF | 8 | 1 | 61 | 1 | 0.13 |
| 24 | Jaquan Brisker | Penn State | SR | S | 8 | 1 | 41 | 0 | 0.13 |
| 24 | Noah Harvey | Mich St | SR | LB | 8 | 1 | 35 | 0 | 0.13 |
| 24 | Gemon Green | Michigan | SR | DB | 8 | 1 | 27 | 0 | 0.13 |
| 24 | Avery Young | Rutgers | JR | DB | 8 | 1 | 16 | 0 | 0.13 |
| 24 | Dedrick Mackey | Purdue | SR | CB | 8 | 1 | 15 | 0 | 0.13 |
| 24 | Jacob Wahlberg | Purdue | SO | LB | 8 | 1 | 7 | 0 | 0.13 |
| 24 | Joey Porter Jr. | Penn State | SO | CB | 8 | 1 | 1 | 0 | 0.13 |
| 24 | Ryan Watts | Ohio State | FR | CB | 8 | 1 | 0 | 0 | 0.13 |
| 24 | Daequan Hardy | Penn State | SO | CB | 8 | 1 | -1 | 0 | 0.13 |
| 24 | Chester Kimbrough | Mich St | JR | CB | 9 | 1 | 62 | 0 | 0.11 |
| 24 | Cody Simon | Ohio State | SO | LB | 9 | 1 | 24 | 0 | 0.11 |
| 24 | Denzel Burke | Ohio State | FR | CB | 9 | 1 | 23 | 1 | 0.11 |
| 24 | Tre Avery | Rutgers | SR | DB | 9 | 1 | 21 | 0 | 0.11 |
| 24 | Tyreem Powell | Rutgers | FR | LB | 9 | 1 | 5 | 0 | 0.11 |
| 24 | Troy Hudetz | N'western | SR | LB | 9 | 1 | 3 | 0 | 0.11 |