2021 American Athletic Conference Leaders Penalties - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | East Carolina | 1 | 3 | 20 | 3.0 | 20.0 |
| 2 | SMU | 1 | 4 | 30 | 4.0 | 30.0 |
| 3 | Houston | 2 | 12 | 84 | 6.0 | 42.0 |
| 4 | Temple | 2 | 16 | 91 | 8.0 | 45.5 |
| 5 | UCF | 2 | 11 | 97 | 5.5 | 48.5 |
| 6 | South Florida | 2 | 8 | 100 | 4.0 | 50.0 |
| 7 | Memphis | 1 | 6 | 55 | 6.0 | 55.0 |
| 8 | Cincinnati | 2 | 17 | 111 | 8.5 | 55.5 |
| 9 | Tulane | 2 | 17 | 157 | 8.5 | 78.5 |
| 10 | Tulsa | 2 | 17 | 161 | 8.5 | 80.5 |