2021 American Athletic Conference Leaders Turnover Margin - Games in October Only through 01/10/2022
| Name | G | Fum. Gain | Int. Gain | Total Gain | Fum. Lost | Int. Lost | Total Lost | Margin | Margin/G | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 5 | 6 | 8 | 14 | 2 | 2 | 4 | 10 | 2.00 |
| 2 | Houston | 4 | 4 | 4 | 8 | 2 | 1 | 3 | 5 | 1.25 |
| 2 | Navy | 5 | 3 | 5 | 8 | 2 | 1 | 3 | 5 | 1.00 |
| 4 | UCF | 5 | 9 | 4 | 13 | 3 | 6 | 9 | 4 | 0.80 |
| 5 | South Florida | 4 | 4 | 5 | 9 | 4 | 3 | 7 | 2 | 0.50 |
| 6 | East Carolina | 4 | 3 | 7 | 10 | 8 | 1 | 9 | 1 | 0.25 |
| 7 | SMU | 4 | 2 | 1 | 3 | 1 | 3 | 4 | -1 | -0.25 |
| 8 | Temple | 4 | 4 | 1 | 5 | 5 | 3 | 8 | -3 | -0.75 |
| 8 | Tulsa | 4 | 2 | 3 | 5 | 2 | 6 | 8 | -3 | -0.75 |
| 10 | Memphis | 4 | 0 | 1 | 1 | 4 | 6 | 10 | -9 | -2.25 |
| 10 | Tulane | 4 | 0 | 1 | 1 | 4 | 6 | 10 | -9 | -2.25 |