2021 American Athletic Conference Leaders Scoring Offense - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Houston | 13 | 63 | 14 | 60 | 0 | 1 | 482 | 37.1 |
| 1 | UCF | 12 | 53 | 8 | 50 | 0 | 1 | 394 | 32.8 |
| 3 | Cincinnati | 11 | 62 | 6 | 59 | 1 | 0 | 451 | 41.0 |
| 3 | SMU | 10 | 54 | 11 | 49 | 2 | 0 | 410 | 41.0 |
| 3 | East Carolina | 10 | 39 | 16 | 35 | 1 | 0 | 319 | 31.9 |
| 3 | Memphis | 11 | 46 | 10 | 36 | 3 | 0 | 348 | 31.6 |
| 3 | Tulane | 8 | 32 | 6 | 27 | 2 | 0 | 241 | 30.1 |
| 3 | Tulsa | 9 | 32 | 16 | 30 | 0 | 0 | 270 | 30.0 |
| 3 | South Florida | 8 | 22 | 9 | 22 | 0 | 0 | 181 | 22.6 |
| 3 | Navy | 9 | 24 | 9 | 24 | 0 | 0 | 195 | 21.7 |
| 3 | Temple | 10 | 23 | 8 | 23 | 0 | 0 | 185 | 18.5 |