2021 American Athletic Conference Leaders Rushing Offense - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 9 | 308 | 1755 | 5.70 | 24 | 34.22 | 195.00 |
| 2 | Houston | 9 | 342 | 1343 | 3.93 | 18 | 38.00 | 149.22 |
| 3 | Navy | 8 | 480 | 1982 | 4.13 | 16 | 60.00 | 247.75 |
| 3 | South Florida | 8 | 320 | 1270 | 3.97 | 16 | 40.00 | 158.75 |
| 3 | SMU | 8 | 263 | 1008 | 3.83 | 16 | 32.88 | 126.00 |
| 6 | East Carolina | 8 | 340 | 1427 | 4.20 | 14 | 42.50 | 178.38 |
| 7 | Tulsa | 8 | 334 | 1501 | 4.49 | 13 | 41.75 | 187.63 |
| 7 | Tulane | 8 | 300 | 1354 | 4.51 | 13 | 37.50 | 169.25 |
| 7 | UCF | 8 | 267 | 1227 | 4.60 | 13 | 33.38 | 153.38 |
| 10 | Memphis | 8 | 269 | 895 | 3.33 | 10 | 33.63 | 111.88 |
| 11 | Temple | 8 | 225 | 832 | 3.70 | 5 | 28.13 | 104.00 |