2021 American Athletic Conference Leaders Passes Defended - All Games through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | UCF | 13 | 11 | 59 | 70 | 5.38 |
| 1 | Cincinnati | 14 | 19 | 51 | 70 | 5.00 |
| 3 | East Carolina | 12 | 15 | 48 | 63 | 5.25 |
| 4 | Memphis | 12 | 9 | 51 | 60 | 5.00 |
| 5 | Houston | 14 | 14 | 43 | 57 | 4.07 |
| 6 | Tulsa | 13 | 11 | 43 | 54 | 4.15 |
| 7 | SMU | 12 | 10 | 38 | 48 | 4.00 |
| 8 | Tulane | 12 | 10 | 31 | 41 | 3.42 |
| 9 | Temple | 12 | 6 | 32 | 38 | 3.17 |
| 10 | South Florida | 12 | 10 | 26 | 36 | 3.00 |
| 11 | Navy | 12 | 7 | 27 | 34 | 2.83 |