2021 American Athletic Conference Leaders Passes Defended - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Marcus Jones | Houston | SR | CB | 12 | 5 | 13 | 18 | 1.50 |
| 2 | Ja'Quan McMillian | ECU | SO | CB | 11 | 4 | 10 | 14 | 1.27 |
| 3 | Quindell Johnson | Memphis | JR | DB | 11 | 1 | 11 | 12 | 1.09 |
| 3 | Greg Rubin | Memphis | FR | DB | 11 | 0 | 12 | 12 | 1.09 |
| 3 | Jaylon Monroe | Tulane | SR | CB | 11 | 0 | 12 | 12 | 1.09 |
| 6 | Coby Bryant | Cincinnati | SR | CB | 13 | 3 | 10 | 13 | 1.00 |
| 6 | Davonte Brown | UCF | SO | DB | 12 | 1 | 11 | 12 | 1.00 |
| 8 | Travon Fuller | Tulsa | SR | CB | 12 | 3 | 8 | 11 | 0.92 |
| 9 | TieNeal Martin | Tulsa | SR | S | 12 | 4 | 6 | 10 | 0.83 |
| 9 | Tyon Davis | Tulsa | SR | CB | 12 | 0 | 10 | 10 | 0.83 |
| 11 | Malik Fleming | ECU | SO | CB | 11 | 2 | 7 | 9 | 0.82 |
| 12 | Justin Hodges | UCF | SO | DB | 10 | 1 | 7 | 8 | 0.80 |
| 12 | Jahari Rogers | SMU | FR | CB | 10 | 0 | 8 | 8 | 0.80 |
| 14 | Bryan Cook | Cincinnati | SR | S | 13 | 2 | 8 | 10 | 0.77 |
| 14 | Damarion Williams | Houston | SR | CB | 13 | 1 | 9 | 10 | 0.77 |
| 16 | Jacobi Francis | Memphis | SR | DB | 11 | 2 | 6 | 8 | 0.73 |
| 17 | Warren Saba | ECU | SR | SAF | 11 | 4 | 3 | 7 | 0.64 |
| 18 | Alex Hogan | Houston | JR | CB | 13 | 2 | 6 | 8 | 0.62 |
| 19 | Arquon Bush | Cincinnati | JR | CB | 12 | 2 | 5 | 7 | 0.58 |
| 20 | Johnny Hodges | Navy | JR | LB | 9 | 1 | 4 | 5 | 0.56 |
| 21 | Rodney Owens | Memphis | SR | DB | 11 | 2 | 4 | 6 | 0.55 |
| 21 | Corey Thornton | UCF | SO | DB | 11 | 0 | 6 | 6 | 0.55 |
| 21 | Bryan Massey | SMU | SO | S | 11 | 0 | 6 | 6 | 0.55 |
| 24 | Michael McMorris | Navy | SR | CB | 12 | 0 | 6 | 6 | 0.50 |
| 24 | Cameron Ruiz | Temple | JR | CB | 10 | 0 | 5 | 5 | 0.50 |
| 26 | Deshawn Pace | Cincinnati | SO | LB | 13 | 4 | 2 | 6 | 0.46 |
| 26 | Ahmad Gardner | Cincinnati | JR | CB | 13 | 2 | 4 | 6 | 0.46 |
| 26 | Myjai Sanders | Cincinnati | SR | DL | 13 | 0 | 6 | 6 | 0.46 |
| 29 | Mekhi LaPointe | S Florida | SR | DB | 11 | 2 | 3 | 5 | 0.45 |
| 29 | Jadon Canady | Tulane | FR | DB | 11 | 2 | 3 | 5 | 0.45 |
| 29 | Manny Walker | Temple | SR | DE | 11 | 1 | 4 | 5 | 0.45 |
| 29 | Ajani Kerr | Tulane | SR | DB | 11 | 0 | 5 | 5 | 0.45 |
| 33 | Jalen Ware | Temple | JR | SAF | 9 | 2 | 2 | 4 | 0.44 |
| 34 | Gervarrius Owens | Houston | JR | S | 12 | 2 | 3 | 5 | 0.42 |
| 34 | Rayuan Lane | Navy | FR | S | 12 | 1 | 4 | 5 | 0.42 |
| 34 | Quadric Bullard | UCF | SO | DB | 12 | 0 | 5 | 5 | 0.42 |
| 37 | M.J. Griffin | Temple | FR | SAF | 10 | 0 | 4 | 4 | 0.40 |
| 38 | Macon Clark | Tulane | JR | S | 11 | 4 | 0 | 4 | 0.36 |
| 38 | Isaac Slade-Matautia | SMU | JR | LB | 11 | 2 | 2 | 4 | 0.36 |
| 38 | Jireh Wilson | ECU | SO | SAF | 11 | 1 | 3 | 4 | 0.36 |
| 38 | Jaise Oliver | Tulsa | SO | S | 11 | 1 | 3 | 4 | 0.36 |
| 38 | Myles Berry | ECU | JR | ILB | 11 | 0 | 4 | 4 | 0.36 |
| 43 | Divaad Wilson | UCF | JR | DB | 12 | 2 | 2 | 4 | 0.33 |
| 43 | Cam Goode | UCF | JR | DL | 12 | 1 | 3 | 4 | 0.33 |
| 43 | Brock Nichols | S Florida | SR | S | 9 | 1 | 2 | 3 | 0.33 |
| 43 | Matthew Hill | S Florida | SO | S | 9 | 1 | 2 | 3 | 0.33 |
| 43 | Amir Tyler | Temple | SR | SAF | 9 | 0 | 3 | 3 | 0.33 |
| 48 | Ja'von Hicks | Cincinnati | SR | S | 13 | 1 | 3 | 4 | 0.31 |
| 49 | Daquan Evans | S Florida | JR | DB | 10 | 0 | 3 | 3 | 0.30 |
| 49 | Alex Odom | Temple | FR | SAF | 10 | 0 | 3 | 3 | 0.30 |
Note: To qualify, player must have played in 75% of his team's games.