2021 American Athletic Conference Leaders Passes Defended - Games on the Road/Neutral Site Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jaylon Monroe | Tulane | SR | CB | 6 | 0 | 10 | 10 | 1.67 | 
| 2 | Marcus Jones | Houston | SR | CB | 8 | 2 | 9 | 11 | 1.38 | 
| 3 | Coby Bryant | Cincinnati | SR | CB | 7 | 1 | 8 | 9 | 1.29 | 
| 4 | Damarion Williams | Houston | SR | CB | 9 | 1 | 7 | 8 | 0.89 | 
| 4 | Greg Rubin | Memphis | FR | DB | 5 | 0 | 7 | 7 | 1.40 | 
| 4 | Tyon Davis | Tulsa | SR | CB | 7 | 0 | 7 | 7 | 1.00 | 
| 7 | Myjai Sanders | Cincinnati | SR | DL | 7 | 0 | 6 | 6 | 0.86 | 
| 8 | Davonte Brown | UCF | SO | DB | 6 | 0 | 5 | 5 | 0.83 | 
| 9 | Ahmad Gardner | Cincinnati | JR | CB | 7 | 2 | 4 | 6 | 0.86 | 
| 9 | TieNeal Martin | Tulsa | SR | S | 7 | 2 | 4 | 6 | 0.86 | 
| 9 | Quindell Johnson | Memphis | JR | DB | 5 | 0 | 4 | 4 | 0.80 | 
| 9 | Jahari Rogers | SMU | FR | CB | 5 | 0 | 4 | 4 | 0.80 | 
| 9 | Cameron Ruiz | Temple | JR | CB | 6 | 0 | 4 | 4 | 0.67 | 
| 14 | Gervarrius Owens | Houston | JR | S | 8 | 2 | 3 | 5 | 0.63 | 
| 14 | Rodney Owens | Memphis | SR | DB | 5 | 1 | 3 | 4 | 0.80 | 
| 14 | Malik Fleming | ECU | SO | CB | 6 | 1 | 3 | 4 | 0.67 | 
| 14 | Rayuan Lane | Navy | FR | S | 6 | 1 | 3 | 4 | 0.67 | 
| 14 | Amir Tyler | Temple | SR | SAF | 5 | 0 | 3 | 3 | 0.60 | 
| 14 | Quadric Bullard | UCF | SO | DB | 6 | 0 | 3 | 3 | 0.50 | 
| 14 | Mekhi LaPointe | S Florida | SR | DB | 6 | 0 | 3 | 3 | 0.50 | 
| 14 | Dorian Williams | Tulane | SO | LB | 6 | 0 | 3 | 3 | 0.50 | 
| 14 | Ajani Kerr | Tulane | SR | DB | 6 | 0 | 3 | 3 | 0.50 | 
| 14 | Michael McMorris | Navy | SR | CB | 6 | 0 | 3 | 3 | 0.50 | 
| 24 | Ja'Quan McMillian | ECU | SO | CB | 6 | 3 | 2 | 5 | 0.83 | 
| 24 | Arquon Bush | Cincinnati | JR | CB | 6 | 2 | 2 | 4 | 0.67 | 
| 24 | Bryan Cook | Cincinnati | SR | S | 7 | 2 | 2 | 4 | 0.57 | 
| 24 | Matthew Hill | S Florida | SO | S | 5 | 1 | 2 | 3 | 0.60 | 
| 24 | Isaac Slade-Matautia | SMU | JR | LB | 6 | 1 | 2 | 3 | 0.50 | 
| 24 | Manny Walker | Temple | SR | DE | 6 | 1 | 2 | 3 | 0.50 | 
| 24 | Ja'von Hicks | Cincinnati | SR | S | 7 | 1 | 2 | 3 | 0.43 | 
| 24 | DaeSean Winston | Temple | JR | SAF | 2 | 0 | 2 | 2 | 1.00 | 
| 24 | Justin Hodges | UCF | SO | DB | 5 | 0 | 2 | 2 | 0.40 | 
| 24 | Jacobi Francis | Memphis | SR | DB | 5 | 0 | 2 | 2 | 0.40 | 
| 24 | Sylvonta Oliver | Memphis | SR | DB | 5 | 0 | 2 | 2 | 0.40 | 
| 24 | Demaurez Bellamy | S Florida | JR | LB | 5 | 0 | 2 | 2 | 0.40 | 
| 24 | Alex Odom | Temple | FR | SAF | 5 | 0 | 2 | 2 | 0.40 | 
| 24 | Larry Brooks | Tulane | JR | S | 5 | 0 | 2 | 2 | 0.40 | 
| 24 | Jeremiah Jean-Baptiste | UCF | JR | LB | 6 | 0 | 2 | 2 | 0.33 | 
| 24 | Cam Goode | UCF | JR | DL | 6 | 0 | 2 | 2 | 0.33 | 
| 24 | Divaad Wilson | UCF | JR | DB | 6 | 0 | 2 | 2 | 0.33 | 
| 24 | Warren Saba | ECU | SR | SAF | 6 | 0 | 2 | 2 | 0.33 | 
| 24 | D.J. Ford | ECU | SR | SAF | 6 | 0 | 2 | 2 | 0.33 | 
| 24 | Gary Wiley | SMU | SR | LB | 6 | 0 | 2 | 2 | 0.33 | 
| 24 | Chace Cromartie | SMU | JR | S | 6 | 0 | 2 | 2 | 0.33 | 
| 24 | Bryan Massey | SMU | SO | S | 6 | 0 | 2 | 2 | 0.33 | 
| 24 | Jaise Oliver | Tulsa | SO | S | 6 | 0 | 2 | 2 | 0.33 | 
| 24 | Malik Vann | Cincinnati | SR | DL | 7 | 0 | 2 | 2 | 0.29 | 
| 24 | David Anenih | Houston | SR | DL | 9 | 0 | 2 | 2 | 0.22 | 
| 49 | Deshawn Pace | Cincinnati | SO | LB | 7 | 3 | 1 | 4 | 0.57 | 
| 49 | Gleson Sprewell | Houston | SR | S | 7 | 2 | 1 | 3 | 0.43 |