2021 Atlantic Coast Conference Leaders Turnover Margin - Games Lost Only through 01/10/2022
| Name | G | Fum. Gain | Int. Gain | Total Gain | Fum. Lost | Int. Lost | Total Lost | Margin | Margin/G | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 3 | 3 | 1 | 4 | 0 | 4 | 4 | 0 | 0.00 |
| 2 | Virginia Tech | 7 | 1 | 4 | 5 | 5 | 2 | 7 | -2 | -0.29 |
| 3 | Louisville | 7 | 1 | 3 | 4 | 4 | 3 | 7 | -3 | -0.43 |
| 3 | Pittsburgh | 3 | 1 | 2 | 3 | 2 | 4 | 6 | -3 | -1.00 |
| 3 | North Carolina State | 3 | 0 | 3 | 3 | 2 | 4 | 6 | -3 | -1.00 |
| 6 | Syracuse | 7 | 1 | 3 | 4 | 5 | 4 | 9 | -5 | -0.71 |
| 6 | Wake Forest | 3 | 3 | 1 | 4 | 2 | 7 | 9 | -5 | -1.67 |
| 8 | Georgia Tech | 9 | 6 | 0 | 6 | 4 | 8 | 12 | -6 | -0.67 |
| 8 | Florida State | 7 | 4 | 7 | 11 | 6 | 11 | 17 | -6 | -0.86 |
| 8 | North Carolina | 7 | 2 | 2 | 4 | 3 | 7 | 10 | -6 | -0.86 |
| 8 | Boston College | 6 | 3 | 3 | 6 | 4 | 8 | 12 | -6 | -1.00 |
| 8 | Virginia | 6 | 2 | 4 | 6 | 4 | 8 | 12 | -6 | -1.00 |
| 13 | Duke | 9 | 4 | 3 | 7 | 9 | 7 | 16 | -9 | -1.00 |
| 13 | Miami (Florida) | 5 | 2 | 2 | 4 | 4 | 9 | 13 | -9 | -1.80 |