2021 Atlantic Coast Conference Leaders Passes Defended - All Games through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 13 | 12 | 54 | 66 | 5.08 |
| 2 | North Carolina State | 12 | 15 | 48 | 63 | 5.25 |
| 2 | Pittsburgh | 14 | 16 | 47 | 63 | 4.50 |
| 4 | Florida State | 12 | 14 | 43 | 57 | 4.75 |
| 5 | Duke | 12 | 8 | 47 | 55 | 4.58 |
| 5 | Virginia | 12 | 8 | 47 | 55 | 4.58 |
| 5 | Louisville | 13 | 10 | 45 | 55 | 4.23 |
| 8 | Wake Forest | 14 | 15 | 39 | 54 | 3.86 |
| 9 | Virginia Tech | 13 | 10 | 42 | 52 | 4.00 |
| 10 | North Carolina | 13 | 11 | 40 | 51 | 3.92 |
| 11 | Boston College | 12 | 10 | 35 | 45 | 3.75 |
| 12 | Miami (Florida) | 12 | 8 | 29 | 37 | 3.08 |
| 13 | Syracuse | 12 | 4 | 30 | 34 | 2.83 |
| 14 | Georgia Tech | 12 | 3 | 24 | 27 | 2.25 |