2021 Atlantic Coast Conference Leaders Turnover Margin - All Games through 01/10/2022
| Name | G | Fum. Gain | Int. Gain | Total Gain | Fum. Lost | Int. Lost | Total Lost | Margin | Margin/G | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Virginia Tech | 13 | 4 | 10 | 14 | 7 | 5 | 12 | 2 | 0.15 |
| 2 | North Carolina State | 12 | 1 | 15 | 16 | 5 | 6 | 11 | 5 | 0.42 |
| 2 | Louisville | 13 | 5 | 10 | 15 | 7 | 6 | 13 | 2 | 0.15 |
| 2 | Syracuse | 12 | 3 | 4 | 7 | 6 | 6 | 12 | -5 | -0.42 |
| 5 | Pittsburgh | 14 | 7 | 16 | 23 | 7 | 8 | 15 | 8 | 0.57 |
| 6 | North Carolina | 13 | 4 | 11 | 15 | 5 | 9 | 14 | 1 | 0.08 |
| 6 | Duke | 12 | 6 | 8 | 14 | 12 | 9 | 21 | -7 | -0.58 |
| 8 | Georgia Tech | 12 | 10 | 3 | 13 | 5 | 10 | 15 | -2 | -0.17 |
| 8 | Miami (Florida) | 12 | 3 | 8 | 11 | 7 | 10 | 17 | -6 | -0.50 |
| 10 | Clemson | 13 | 8 | 12 | 20 | 8 | 11 | 19 | 1 | 0.08 |
| 10 | Boston College | 12 | 7 | 10 | 17 | 7 | 11 | 18 | -1 | -0.08 |
| 12 | Florida State | 12 | 6 | 14 | 20 | 9 | 12 | 21 | -1 | -0.08 |
| 12 | Virginia | 12 | 6 | 8 | 14 | 6 | 12 | 18 | -4 | -0.33 |
| 14 | Wake Forest | 14 | 14 | 15 | 29 | 5 | 15 | 20 | 9 | 0.64 |