2021 Atlantic Coast Conference Leaders Tackles For Loss Allowed - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Louisville | 10 | 50.0 | 169 | 5.00 |
| 2 | Clemson | 11 | 58.0 | 222 | 5.27 |
| 3 | North Carolina State | 9 | 50.0 | 225 | 5.56 |
| 4 | Boston College | 9 | 65.0 | 229 | 7.22 |
| 5 | Wake Forest | 11 | 65.0 | 242 | 5.91 |
| 6 | Miami (Florida) | 10 | 65.0 | 244 | 6.50 |
| 7 | Duke | 10 | 71.0 | 248 | 7.10 |
| 8 | Virginia Tech | 10 | 56.0 | 258 | 5.60 |
| 9 | Virginia | 9 | 57.0 | 268 | 6.33 |
| 10 | Syracuse | 9 | 65.0 | 275 | 7.22 |
| 11 | Georgia Tech | 9 | 55.0 | 280 | 6.11 |
| 12 | Florida State | 9 | 65.0 | 292 | 7.22 |
| 13 | Pittsburgh | 11 | 63.0 | 301 | 5.73 |
| 14 | North Carolina | 10 | 80.0 | 336 | 8.00 |