2021 Atlantic Coast Conference Leaders Tackles For Loss Allowed - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Clemson | 4 | 22.0 | 81 | 5.50 |
| 2 | Virginia Tech | 2 | 12.0 | 51 | 6.00 |
| 2 | Pittsburgh | 3 | 18.0 | 105 | 6.00 |
| 2 | Louisville | 5 | 30.0 | 98 | 6.00 |
| 5 | Virginia | 4 | 26.0 | 136 | 6.50 |
| 6 | North Carolina State | 2 | 14.0 | 55 | 7.00 |
| 7 | Miami (Florida) | 4 | 30.0 | 122 | 7.50 |
| 8 | Wake Forest | 3 | 24.0 | 105 | 8.00 |
| 8 | Florida State | 4 | 32.0 | 163 | 8.00 |
| 10 | Boston College | 3 | 25.0 | 95 | 8.33 |
| 11 | North Carolina | 4 | 34.0 | 108 | 8.50 |
| 12 | Duke | 2 | 18.0 | 74 | 9.00 |
| 12 | Georgia Tech | 4 | 36.0 | 199 | 9.00 |
| 14 | Syracuse | 4 | 37.0 | 134 | 9.25 |