2021 Atlantic Coast Conference Leaders Opponent Penalties - Games Lost Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 3 | 30 | 286 | 10.0 | 95.3 |
| 2 | Florida State | 7 | 60 | 499 | 8.6 | 71.3 |
| 3 | Miami (Florida) | 5 | 42 | 383 | 8.4 | 76.6 |
| 4 | Pittsburgh | 3 | 25 | 224 | 8.3 | 74.7 |
| 5 | Wake Forest | 3 | 23 | 218 | 7.7 | 72.7 |
| 5 | North Carolina State | 3 | 23 | 176 | 7.7 | 58.7 |
| 7 | Boston College | 6 | 45 | 414 | 7.5 | 69.0 |
| 8 | Duke | 9 | 61 | 478 | 6.8 | 53.1 |
| 9 | Virginia | 6 | 40 | 335 | 6.7 | 55.8 |
| 10 | Virginia Tech | 7 | 45 | 373 | 6.4 | 53.3 |
| 11 | Louisville | 7 | 42 | 355 | 6.0 | 50.7 |
| 12 | Georgia Tech | 9 | 50 | 467 | 5.6 | 51.9 |
| 13 | Syracuse | 7 | 38 | 351 | 5.4 | 50.1 |
| 14 | North Carolina | 7 | 35 | 286 | 5.0 | 40.9 |