2021 Atlantic Coast Conference Leaders Passing Defense - On 3rd Down, 10+ Yards To Go through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Florida State | 12 | 34 | 14 | 41.2 | 220 | 3 | 2 | 112.90 | 55 | 6 | 5 | 3 |
| 2 | Duke | 12 | 31 | 14 | 45.2 | 251 | 3 | 1 | 138.65 | 48 | 9 | 7 | 2 |
| 3 | Clemson | 13 | 48 | 22 | 45.8 | 204 | 0 | 2 | 73.20 | 22 | 6 | 3 | 0 |
| 4 | North Carolina | 11 | 37 | 18 | 48.6 | 178 | 1 | 1 | 92.57 | 24 | 6 | 6 | 0 |
| 5 | Boston College | 10 | 18 | 9 | 50.0 | 148 | 0 | 0 | 119.06 | 54 | 2 | 3 | 1 |
| 6 | Virginia | 10 | 24 | 14 | 58.3 | 191 | 2 | 1 | 144.35 | 35 | 7 | 5 | 2 |
| 7 | Wake Forest | 11 | 32 | 19 | 59.4 | 224 | 2 | 1 | 132.56 | 23 | 10 | 8 | 0 |
| 8 | Miami (Florida) | 12 | 46 | 28 | 60.9 | 244 | 0 | 1 | 101.07 | 23 | 9 | 6 | 0 |
| 9 | North Carolina State | 12 | 45 | 28 | 62.2 | 309 | 0 | 6 | 93.23 | 34 | 12 | 9 | 1 |
| 10 | Virginia Tech | 13 | 45 | 29 | 64.4 | 370 | 2 | 3 | 134.84 | 30 | 11 | 7 | 6 |
| 11 | Pittsburgh | 14 | 49 | 32 | 65.3 | 355 | 2 | 4 | 123.31 | 57 | 9 | 7 | 2 |
| 12 | Georgia Tech | 11 | 28 | 19 | 67.9 | 289 | 1 | 0 | 166.34 | 63 | 8 | 7 | 2 |
| 13 | Syracuse | 10 | 22 | 15 | 68.2 | 173 | 1 | 0 | 149.24 | 25 | 6 | 5 | 2 |
| 14 | Louisville | 12 | 38 | 26 | 68.4 | 395 | 1 | 3 | 148.64 | 64 | 13 | 12 | 3 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||