2021 Atlantic Coast Conference Leaders Passing Defense - In The 4th Quarter through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 12 | 106 | 55 | 51.9 | 589 | 4 | 3 | 105.36 | 31 | 30 | 13 | 4 |
| 2 | Virginia Tech | 13 | 97 | 46 | 47.4 | 597 | 5 | 5 | 105.82 | 55 | 23 | 15 | 7 |
| 3 | Clemson | 13 | 133 | 76 | 57.1 | 775 | 3 | 1 | 112.03 | 62 | 34 | 18 | 4 |
| 4 | Syracuse | 12 | 64 | 38 | 59.4 | 402 | 2 | 3 | 113.07 | 35 | 17 | 8 | 5 |
| 5 | North Carolina | 12 | 98 | 54 | 55.1 | 632 | 5 | 5 | 115.91 | 64 | 34 | 14 | 6 |
| 6 | Miami (Florida) | 12 | 96 | 54 | 56.3 | 616 | 3 | 2 | 116.29 | 59 | 27 | 10 | 5 |
| 7 | Boston College | 11 | 61 | 35 | 57.4 | 420 | 2 | 2 | 119.47 | 54 | 17 | 8 | 3 |
| 8 | Pittsburgh | 14 | 101 | 61 | 60.4 | 790 | 4 | 5 | 129.27 | 46 | 32 | 19 | 9 |
| 9 | Florida State | 12 | 94 | 50 | 53.2 | 634 | 7 | 2 | 130.17 | 59 | 28 | 14 | 8 |
| 10 | Virginia | 12 | 101 | 59 | 58.4 | 771 | 5 | 1 | 136.91 | 62 | 34 | 17 | 7 |
| 11 | Wake Forest | 13 | 117 | 68 | 58.1 | 811 | 10 | 3 | 139.43 | 75 | 36 | 16 | 6 |
| 12 | Georgia Tech | 11 | 78 | 44 | 56.4 | 627 | 6 | 2 | 144.18 | 63 | 27 | 17 | 6 |
| 13 | Louisville | 13 | 96 | 65 | 67.7 | 701 | 9 | 4 | 151.66 | 34 | 36 | 20 | 3 |
| 14 | Duke | 11 | 68 | 41 | 60.3 | 694 | 8 | 1 | 181.90 | 63 | 27 | 16 | 9 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||