2021 Atlantic Coast Conference Leaders Rushing - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Israel Abanikanda | Pittsburgh | SO | RB | 2 | 14 | 71 | 5.07 | 2 | 7.00 | 35.50 |
| 2 | Trevion Cooley | Louisville | FR | RB | 1 | 18 | 92 | 5.11 | 1 | 18.00 | 92.00 |
| 2 | British Brooks | N Carolina | SR | RB | 1 | 5 | 72 | 14.40 | 1 | 5.00 | 72.00 |
| 2 | Malik Cunningham | Louisville | JR | QB | 1 | 12 | 66 | 5.50 | 1 | 12.00 | 66.00 |
| 2 | Will Shipley | Clemson | FR | RB | 1 | 18 | 61 | 3.39 | 1 | 18.00 | 61.00 |
| 2 | Justice Ellison | Wk Forest | FR | RB | 2 | 13 | 64 | 4.92 | 1 | 6.50 | 32.00 |
| 2 | Kenny Pickett | Pittsburgh | SR | QB | 1 | 6 | 20 | 3.33 | 1 | 6.00 | 20.00 |
| 2 | Nick Patti | Pittsburgh | JR | QB | 2 | 3 | 27 | 9.00 | 1 | 1.50 | 13.50 |
| 2 | Connor Blumrick | Va Tech | JR | QB | 1 | 15 | 11 | 0.73 | 1 | 15.00 | 11.00 |
| 2 | Sam Hartman | Wk Forest | SO | QB | 2 | 17 | 21 | 1.24 | 1 | 8.50 | 10.50 |