2021 Atlantic Coast Conference Leaders Passing - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brennan Armstrong | Virginia | JR | QB | 3 | 142 | 91 | 64.1 | 1231 | 8.7 | 9 | 4 | 152.20 | 47.3 | 410.3 |
| 2 | Devin Leary | NC State | SO | QB | 2 | 103 | 69 | 67.0 | 646 | 6.3 | 8 | 2 | 141.42 | 51.5 | 323.0 |
| 3 | Tyler Van Dyke | Miami (Fl) | FR | QB | 3 | 76 | 57 | 75.0 | 751 | 9.9 | 7 | 1 | 185.78 | 25.3 | 250.3 |
| 4 | Sam Hartman | Wk Forest | SO | QB | 3 | 136 | 68 | 50.0 | 815 | 6.0 | 6 | 8 | 103.14 | 45.3 | 271.7 |
| 4 | Jordan Travis | FSU | SO | QB | 3 | 47 | 28 | 59.6 | 413 | 8.8 | 6 | 4 | 158.49 | 15.7 | 137.7 |
| 6 | Sam Howell | N Carolina | JR | QB | 4 | 116 | 76 | 65.5 | 1000 | 8.6 | 5 | 3 | 146.99 | 29.0 | 250.0 |
| 6 | Garrett Shrader | Syracuse | SO | QB | 4 | 108 | 57 | 52.8 | 631 | 5.8 | 5 | 2 | 113.44 | 27.0 | 157.8 |
| 8 | Kenny Pickett | Pittsburgh | SR | QB | 2 | 72 | 45 | 62.5 | 555 | 7.7 | 4 | 0 | 145.58 | 36.0 | 277.5 |
| 8 | Malik Cunningham | Louisville | JR | QB | 5 | 131 | 76 | 58.0 | 1038 | 7.9 | 4 | 3 | 130.07 | 26.2 | 207.6 |
| 10 | D'Eriq King | Miami (Fl) | SR | QB | 2 | 89 | 61 | 68.5 | 567 | 6.4 | 3 | 4 | 124.19 | 44.5 | 283.5 |
| 10 | DJ Uiagalelei | Clemson | SO | QB | 4 | 107 | 54 | 50.5 | 625 | 5.8 | 3 | 5 | 99.43 | 26.8 | 156.3 |
| 12 | Jeff Sims | Ga Tech | FR | QB | 1 | 33 | 24 | 72.7 | 359 | 10.9 | 2 | 2 | 171.99 | 33.0 | 359.0 |
| 13 | Dennis Grosel | BC | SR | QB | 2 | 79 | 44 | 55.7 | 505 | 6.4 | 1 | 3 | 105.98 | 39.5 | 252.5 |
| 13 | Braxton Burmeister | Va Tech | JR | QB | 2 | 62 | 26 | 41.9 | 318 | 5.1 | 1 | 2 | 83.89 | 31.0 | 159.0 |
| 13 | Davis Beville | Pittsburgh | SO | QB | 1 | 18 | 14 | 77.8 | 149 | 8.3 | 1 | 1 | 154.54 | 18.0 | 149.0 |
| 13 | Gunnar Holmberg | Duke | SR | QB | 2 | 41 | 26 | 63.4 | 284 | 6.9 | 1 | 0 | 129.66 | 20.5 | 142.0 |
| 13 | McKenzie Milton | FSU | SR | QB | 3 | 67 | 38 | 56.7 | 400 | 6.0 | 1 | 3 | 102.84 | 22.3 | 133.3 |
| 13 | Riley Leonard | Duke | FR | QB | 2 | 19 | 8 | 42.1 | 108 | 5.7 | 1 | 1 | 96.70 | 9.5 | 54.0 |
| 13 | Evan Conley | Louisville | SO | QB | 3 | 12 | 7 | 58.3 | 63 | 5.3 | 1 | 0 | 129.93 | 4.0 | 21.0 |
| 13 | Phil Jurkovec | BC | JR | QB | 1 | 11 | 3 | 27.3 | 19 | 1.7 | 1 | 2 | 35.42 | 11.0 | 19.0 |
| 13 | Will Shipley | Clemson | FR | RB | 4 | 1 | 1 | 100.0 | 2 | 2.0 | 1 | 0 | 446.80 | 0.3 | 0.5 |