2021 Atlantic Coast Conference Leaders Passing - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Sam Howell | N Carolina | JR | QB | 3 | 80 | 57 | 71.3 | 898 | 11.2 | 5 | 1 | 183.67 | 26.7 | 299.3 |
| 2 | Brennan Armstrong | Virginia | JR | QB | 3 | 101 | 70 | 69.3 | 1081 | 10.7 | 11 | 3 | 189.22 | 33.7 | 360.3 |
| 3 | Kenny Pickett | Pittsburgh | SR | QB | 4 | 132 | 98 | 74.2 | 1342 | 10.2 | 15 | 1 | 195.62 | 33.0 | 335.5 |
| 4 | Sam Hartman | Wk Forest | SO | QB | 4 | 120 | 81 | 67.5 | 1194 | 10.0 | 12 | 0 | 184.08 | 30.0 | 298.5 |
| 5 | Gunnar Holmberg | Duke | SR | QB | 4 | 129 | 93 | 72.1 | 1140 | 8.8 | 3 | 2 | 150.90 | 32.3 | 285.0 |
| 6 | Malik Cunningham | Louisville | JR | QB | 5 | 139 | 85 | 61.2 | 1086 | 7.8 | 4 | 3 | 131.96 | 27.8 | 217.2 |
| 7 | Devin Leary | NC State | SO | QB | 4 | 140 | 92 | 65.7 | 1045 | 7.5 | 8 | 2 | 144.41 | 35.0 | 261.3 |
| 7 | Tommy DeVito | Syracuse | JR | QB | 3 | 52 | 32 | 61.5 | 388 | 7.5 | 1 | 2 | 122.88 | 17.3 | 129.3 |
| 7 | Dennis Grosel | BC | SR | QB | 4 | 64 | 41 | 64.1 | 477 | 7.5 | 4 | 2 | 141.05 | 16.0 | 119.3 |
| 7 | Jordan Travis | FSU | SO | QB | 4 | 61 | 32 | 52.5 | 455 | 7.5 | 3 | 4 | 118.24 | 15.3 | 113.8 |
| 11 | Braxton Burmeister | Va Tech | JR | QB | 4 | 112 | 65 | 58.0 | 761 | 6.8 | 4 | 1 | 125.11 | 28.0 | 190.3 |
| 12 | Jordan Yates | Ga Tech | FR | QB | 4 | 85 | 51 | 60.0 | 558 | 6.6 | 5 | 1 | 132.21 | 21.3 | 139.5 |
| 13 | D'Eriq King | Miami (Fl) | SR | QB | 3 | 122 | 81 | 66.4 | 767 | 6.3 | 3 | 4 | 120.75 | 40.7 | 255.7 |
| 14 | DJ Uiagalelei | Clemson | SO | QB | 5 | 156 | 84 | 53.8 | 876 | 5.6 | 2 | 5 | 98.84 | 31.2 | 175.2 |
Note: To qualify, player must have played in 75% of his team's games and have a minimum of 15.0 pass attempts per game played.