2021 Atlantic Coast Conference Leaders Interceptions - Games at Home Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jermaine Waller | Va Tech | JR | DB | 7 | 3 | 56 | 1 | 0.43 |
| 1 | Drake Thomas | NC State | SO | LB | 7 | 3 | 0 | 1 | 0.43 |
| 1 | Damarri Mathis | Pittsburgh | SR | DB | 7 | 2 | 50 | 1 | 0.29 |
| 1 | Jahmin Muse | BC | SR | DB | 4 | 1 | 22 | 1 | 0.25 |
| 1 | SirVocea Dennis | Pittsburgh | JR | LB | 6 | 1 | 50 | 1 | 0.17 |
| 1 | Jarvis Brownlee, Jr. | FSU | FR | DB | 7 | 1 | 70 | 1 | 0.14 |
| 1 | Jaylin Alderman | Louisville | FR | LB | 7 | 1 | 66 | 1 | 0.14 |